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eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
Bieżący numer Archiwum Filmy Artykuły w druku O czasopiśmie Suplementy Rada naukowa Recenzenci Bazy indeksacyjne Prenumerata Kontakt Zasady publikacji prac Opłaty publikacyjne Standardy etyczne i procedury
Panel Redakcyjny
Zgłaszanie i recenzowanie prac online
SCImago Journal & Country Rank
4/2008
vol. 110
 
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Artykuł oryginalny

Czynniki ryzyka AMD i jaskry – obserwacje własne

Joanna Wierzbowska
1
,
Małgorzata Figurska
1
,
Andrzej Stankiewicz
1
,
Janusz Sierdziński
2

  1. Z Kliniki Okulistycznej Wojskowego Instytutu Medycznego w Warszawie
  2. Z Zakładu Informatyki Medycznej i Telemedycyny Uniwersytetu Medycznego w Warszawie
Data publikacji online: 2008/12/20
Pełna treść artykułu Pobierz cytowanie
 


Purpose: To assess the differences between the prevalence of risk factors in patients with age- related macular degeneration

(AMD), with glaucoma and with both diseases.

Material and methods: The study included 255 patients, 156 F/99 M, in age 30 to 92 years, mean age 70.9 years. They were divided into 3 groups: AMD Group (83 patients, 46 F/37 M, mean age 71.5), Glaucoma Group (34 patients, 17 F/17 M, mean age

67.1) and AMD + Glaucoma Group (138 patients, 93 F/ 45 M, mean age 70.9). In all groups age, sex, family history of AMD

and glaucoma, hypertension, hypotension, hypercholesterolemia, diabetes, coronary heart disease, vasospasm (cold hands),

migraine, heart failure and stroke in anamnesis, smoking, type of diet (high or low fat intake, high or low vitamin intake), UV

exposition, cataract surgery in anamnesis, bright-coloured iris, disc hemorrhages and peripapillary atrophy were determined,

and compared between them. T-student test, ANOVA, Bonferoni, Kruskall-Wallis and chi-square tests and logistic analysis (likelihood ratio chi-square) were used for statistical analysis.

Results: Family history of glaucoma were higher in the Glaucoma Group (odds ratio OR 9.0 p=0.004) than in the AMD Group

(odds ratio OR 9.0 p=0.004) and than in the AMD + Glaucoma Group (OR 3.01 p=0.001). Disc hemorrhages were higher in

the Glaucoma Group (OR 13.0 p=0,020) than in the AMD Group (OR 13.0 p=0.020). High fat intake in diet were lower in the

Glaucoma Group as compared to the AMD Group (OR 0.5 p=0,03). Cholesterol high level and UV exposition were lower in

the Glaucoma Group than in the AMD + Glaucoma Group (OR 0.278 p=0,020 and OR 0.23 p=0,040 respectively). Coronary

heart disease and peripapillary atrophy were lower in the AMD Group as compared to the AMD + Glaucoma Group (OR 0.43

p=0.004 and OR 0.5 p= 0.040).

Conclusions: The study has found that high fat intake in diet was higher in the patients with AMD and family history of glaucoma, and disc hemorrhages were higher in the patients with glaucoma. The following risk factors: high level of cholesterol, UV

exposition, coronary heart disease and peripapillary atrophy, were higher in the patients with co-existing both diseases.
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