twitter
en ENGLISH
eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
Bieżący numer Archiwum Filmy Artykuły w druku O czasopiśmie Suplementy Rada naukowa Recenzenci Bazy indeksacyjne Prenumerata Kontakt Zasady publikacji prac Opłaty publikacyjne Standardy etyczne i procedury
Panel Redakcyjny
Zgłaszanie i recenzowanie prac online
SCImago Journal & Country Rank
2/2022
vol. 124
 
Poleć ten artykuł:
Udostępnij:
streszczenie artykułu:
Artykuł oryginalny

Assessment of pranoprofen ophthalmic solution 0.1% application for non-infectious conjunctivitis in patients with symptoms of dry eye disease

Agata Brązert
1
,
Jarosław Kocięcki
1

  1. Department of Ophthalmology, Poznan University of Medical Sciences, Poland
KLINIKA OCZNA 2022, 124, 2: 92–98
Data publikacji online: 2022/06/14
Pełna treść artykułu Pobierz cytowanie
 
Metryki PlumX:


Introduction
Dry eye disease (DED) can be caused by many factors and conditions. It is a multifactorial disease, in which ocular surface inflammation plays an important role in the pathogenesis.

Aim of the study
To assess efficacy of pranoprofen ophthalmic solution 0.1% applied for treatment of non-infectious conjunctivitis in patients with symptoms of dry eye disease.

Material and methods
Prospective, single-arm, open, noninterventional study. Near and distant best corrected visual acuity, intraocular pressure measurement with air-puff tonometer as well as Schirmer I test, bulbar hyperemia, conjunctival edema, tear break-up time (TBUT), cornea and conjunctival staining score and lid-parallel conjunctival folds (LIPCOF) were assessed. Slit lamp examination included anterior segment and fundus examination. Patients were treated with pranoprofen ophthalmic solution 0.1% 4 times a day for 2-4 weeks.

Results
13 patients were screened, and 12 fulfilled inclusion criteria. The most significant improvement was observed in the change of subjective dry eye symptoms reported by the patients (equal for all OSDI sections). Improvement was observed in conjunctival hyperemia as well as degree of conjunctival and corneal staining (Oxford scale). There was no change in TBUT and LIPCOF. There were two non-serious adverse events reported during the course of the study.

Conclusions
Pranoprofen ophthalmic solution 0.1% is an effective and safe treatment for non-infectious conjunctivitis with mild to moderate dry eye symptoms. Add-on treatment with pranoprofen ophthalmic solution 0.1% greatly improved the patient’s subjective symptoms (OSDI score).

© 2024 Termedia Sp. z o.o.
Developed by Bentus.